Health » The Olive Ridley Crawl

High fructose corn syrup makes you fat

Mar 222010

This well designed and well executed study provides rather conclusive proof that High Fructose Corn Syrup, the sweetener most commonly used in North America, makes you gain weight in a way not explained by calories alone. These rats gained more weight on HFCS compared to a sucrose (regular sugar) diet even though they were fed the same calories. The effect was seen in the short term and in the long term, and abdominal fat increased the most. Gut fat, if you did not know is related to the infamous metabolic syndrome, causing diabetes, hypertension, coronary disease, etc.

High-fructose corn syrup (HFCS) accounts for as much as 40% of caloric sweeteners used in the United States. Some studies have shown that short-term access to HFCS can cause increased body weight, but the findings are mixed. The current study examined both short- and long-term effects of HFCS on body weight, body fat, and circulating triglycerides. In Experiment 1, male Sprague–Dawley rats were maintained for short term (8 weeks) on (1) 12 h/day of 8% HFCS, (2) 12 h/day 10% sucrose, (3) 24 h/day HFCS, all with ad libitum rodent chow, or (4) ad libitum chow alone. Rats with 12-h access to HFCS gained significantly more body weight than animals given equal access to 10% sucrose, even though they consumed the same number of total calories, but fewer calories from HFCS than sucrose. In Experiment 2, the long-term effects of HFCS on body weight and obesogenic parameters, as well as gender differences, were explored. Over the course of 6 or 7 months, both male and female rats with access to HFCS gained significantly more body weight than control groups. This increase in body weight with HFCS was accompanied by an increase in adipose fat, notably in the abdominal region, and elevated circulating triglyceride levels. Translated to humans, these results suggest that excessive consumption of HFCS may contribute to the incidence of obesity.

Miriam E. Bocarsly, Elyse S. Powell, Nicole M. Avena, Bartley G. Hoebel. High-fructose corn syrup causes characteristic of obesity in rats: Increased body weight, body fat and triglyceride levels. Pharmacology Biochemistry and Behavior, 2010; DOI: 10.1016/j.pbb.2010.02.012

For a more layman friendly summary of the article, read the sciencedaily release.

Do reconsider your food habits to avoid HFCS. Note that this whole corn syrup boondongle is made possible by the US government’s insistence on providing billion dollar subsidies to its farmers to grow corn while imposing tariffs on cane sugar from the tropics to make it less attractive. Free trade, my A$$.

Thanks to Tom Laskawy at grist for the blog post.

Al Franken is good for health

Environment, Health No Responses »

Sep 302009

You know what's in your food and many beauty products. Senator Al Franken wants to make it possible to see exactly what's in your household cleaning products as well.The Minnesota Democrat introduced a bill in the U.S. Senate requiring producers to fully disclose all ingredients on their product labels, including those suspected of causing long-term harm. Currently the warnings on cleansers are designed to prevent immediate harm due to swallowing, splashing in eyes or other unintended uses.

via Kare 11

It would seem common sense to have information on labels, especially on the harsh and powerful chemicals we use every day. You may not understand what they mean, or how to pronounce the chemical names, but you don’t have to! Organizations such as the Environmental Working Group have extensive information on common high volume chemicals so people can match what they see on the label with what they would like to avoid.

But it is not the law of the land in the US, or Canada for that matter. Al Franken, comedian, talk show host and an intelligent man turned senator would like to change that in the US. Of course, we in Canada would benefit as well.

Chemical manufacturers aren’t having any of this.

There’s always a concern about turning labels into encyclopedias,” Brian Sansoni of the Soap and Detergent Association, in Washington, D.C., told KARE Tuesday.

Pretty insulting, claiming that your consumer does not like encyclopedias, or is not capable of reading and googling.

Information helps drive consumers to safer alternatives. If you see two cleaners, both of which claim to work equally well, a quick read of the ingredients will drive you to the safer (or simpler) choice. Clearly, sale by obfuscation is the preferred marketing strategy here.

If I were American, I would call my senator/congressperson and ask them to support Al Franken.

Sugar Pills, now more effective!

Health, Pharma 2 Responses »

Sep 032009

Well, all sugar is not bad for you. Apparently, when given to you in pill form by someone wearing a white coat with a pleasant demeanour, it can cure all kinds of ills.

It’s not that the old meds are getting weaker, drug developers say. It's as if the placebo effect is somehow getting stronger.The fact that an increasing number of medications are unable to beat sugar pills has thrown the industry into crisis. The stakes could hardly be higher. In today's economy, the fate of a long-established company can hang on the outcome of a handful of tests.

Via Wired

An interesting article that takes the reader through a recent history of placebos, why they seem to work better now than they used to, and tangentially, why the competitive research paradigm of the pharmaceutical industry delayed recognition, and continues to delay possible fixes and therapies.

A few things about the placebo effect:

There appears to be a physiological and neurological basis to the effect, something that can actually be turned off by deactivating the body’s natural production of opioids.
This effect is triggered by various patient stimuli, including exposure to advertising, faith in the medicine, doctor bedside manner, etc. It appears that for minor ailments, these effects could be as strong as the medication prescribed.
It is not short lived, the effects can linger well after consumption of sugar pills.
Despite all this, the article states that we are no closer to finding the most appropriate way to administer placebos (Hmm, or are we? Read on!).

Pharmaceutical companies conduct hundreds of clinical trials every year. They are not required to publish them in most countries, so negative results, failures, etc. which reflect badly on the company’s stock price are routinely hushed up. This means that the mounds of data that show tested drugs as no better than placebo are not accessible for research. This is one of the greatest drawbacks of competitive research paradigms, the lack of cooperation, the inefficiency that comes from duplication of negative results, and the lack of statistical power that comes from inability to use all the data available. In a milieu where knowledge = stock price, this is the logical approach, but something to note next time an Ayn Rand acolyte comes bleating to you about the beauty and perfection of the market. You might ask “What are some options to the current patent exclusivity driven regime”? My favourite economist Dean Baker of the Center for Economics and Policy Research has written extensively about the drug development process and alternatives in his excellent (and free to download) book The Conservative Nanny State, I suggest reading at least the chapter on drug development and patents!

Anyway, back to placebos, what to do? How to administer sugar pills in a quasi-official setting for minor ailments. It’s almost like you need a parallel paradigm of medicine that dispenses sugar pills that did not have to go through double blind randomised clinical trials. it would help if this paradigm uses vaguely scientific terminology while doing very little harm. It would work in conjunction with the conventional approach, not in competition so there is little danger of people taking sugar pills for malaria!

I give you, Homeopathy!!! This blog(ger) is no stranger to this wonderful form of medicine, involving concepts such as the memory of water, similars, dilution, etc. When I wrote about homeopathy last year, it was more in relation to the psychological aspects of my experience with it. I (and I assume you did not click through to read!) wrote about my parents’ great and enduring relationship with their homeopath, and the benefits it brought them. Back in India this time around, it was suggested that I take some homeopathy for a cold I was developing, which I did (yum, sugar!). The cold went away in a few days There was some swine flu medicine being passed around as well (I did not partake), which worked too, nobody at home got swine flu

So, how to make it work? It already works in India because belief in the efficacy of homeopathy is well established. As long as the homeopath is well qualified in basic diagnosis, and crucially, knows when to punt the patient into conventional therapy, the system works to a certain extent. But what about a society with no such foundation? Do you go to a clinic with both an allopath and a homeopath, and if your ailment is one where placebo works about as well, let the homeopath make some well diluted similars for you to consume? How to settle turf wars? Would it be better for the allopath to ~~feign~~ develop an expertise in homeopathy and make that work for her in treating the patient? Would they apply the most important lessons in homeopathic treatment, Listen, Empathise, Soothe?

I don’t know. It is not my nature to believe in sugar pills, faith, or advertising. So it is hard for me to say what would work. But given that sugar pills work well, it is vital for society to find a way.

Soda = Fat

corn, Health 1 Response »

Sep 022009

Sodat Fat

From The New York Department of Health

Try this experiment at home: Take two and a half cups of water, add 15-20 teaspoons of sugar and stir to dissolve. If you haven’t broken your wrist with all this action, take a sip or two, or gulp it down. No worries, you’ve just had all the nutrition in a typical soda!

That’s the message the NY Department of health is sending out with its new PR campaign against soda. Pretty gross and effective, I must say, though I would go one further and put it on every label of Coke, now wouldn’t that be nice!

NC Smoking ban now inevitable?

Environment, Health 2 Responses »

May 082009

Well, it has taken less than a decade (I am a pessimist), but looks like smoking in bars and restaurants may finally be over and done with in my old home state of NC.

Note that there is currently a HUGE loophole in the senate version of the bill, it permits smoking in “private clubs”. Many bars in NC designate themselves as “private clubs” to circumvent prohibition era (or thereabouts) laws that mandate liquor serving establishments to get a certain percentage of their revenue from food. So, my favourite Chapel Hill drinking establishment, The Dead Mule (no website, sorry!) is supposedly a “private club” – You supposedly pay a one time membership fee (usually less than 5 bucks), and are supposed to “sign in” any members and guests. This was all a farce anyway, and the Mule got extremely smoky, it was quite disgusting after a while.

One hopes that the final bill will make the ban universal. Bans like this work best when they don’t favour one group of establishments over the other for no real reason. The people who work at the Dead Mule are equally entitled to clean air.

1.5 cautious cheers, let’s see what happens in the end…

The state Senate voted Thursday to ban smoking in bars and restaurants in North Carolina. It set the stage for what would be a historic prohibition of a product that created thousands of jobs, built Duke and Wake Forest universities and has long been an integral part of the culture in the nation's top tobacco-producing state.

House members passed a tougher version last month, meaning that lawmakers will still have to work out a compromise, assuming the Senate passes the measure in a second vote on Monday. The bill passed Thursday by an eight-vote margin, 26-18, so that seems likely.

via State Senate OKs smoking ban – Politics – News & Observer.

Circumcision and AIDS – Revisited

culture, Health, public health No Responses »

Apr 162009

A post I wrote quite a while back on circumcision and AIDS remains my most commented post ever. In it (if you’re too lazy to click) I said that while research indicating a reduction in HIV infection in circumcised men was promising, there were a couple of concerns. One, that this could be a distraction from the single most effective prevention measure (no, not abstinence!), condom use. And two, that in certain cultures, especially among Hindus, this would be an absolute no no because circumcision is identified with being Muslim.

Anyway, in a review article, the Cochrane Centre in South Africa summarizes results from a meta analysis of a number of trials indicating a 50% reduction in HIV incidence among circumcised males. At this point in time, it is clear that circumcision is effective in reducing HIV incidence among heterosexual males. Based on this, the institute encourages the widespread use of circumcision as an AIDS prevention strategy.

So, am I still circumspect? Absolutely. I am still concerned that this research will be misinterpreted in a way that discourages condom use. In fact, the authors note that circumcised men indulged in more risky behaviour. Also, the incidence of HIV in the women these men were sleeping with increased from 9.6% to 13.8%, a 40% uptick. This increase was not statistically significant. No arguing with that, though the study was stopped early once it was clear that the men were helped, never mind the women, or reaching statistical significance in their case.

Given that it is very unclear what the effects of circumcision are on anything other than circumcised penises, which are only one half of the equation (or less!), I don’t think it is responsible to call for widespread use of circumcision as a public health strategy for the prevention of HIV until its effects on the other parties are known. While people are aware of this issue, I don’t think the science or the cultural landscape promote the use of circumcision as a HIV prevention strategy until its proven that women are not at risk from increased HIV incidence either biologically from a yet unknown mechanism, or socially from increased risk taking.

Men have more power in most societies to demand and receive sex on their terms. So the male centric nature of this research, and the conclusions drawn are disturbing. How irresponsible is it to encourage a public health strategy that appears to increase risk taking behaviour among men when the effects on the women are yet unknown, with only a statistically “insignificant” 40% increase in HIV incidence among women being observed?

I am. for very good reason, still circumspect on circumcision.

Whisky flavoured condoms courtesy bruno girin’s photostream used under a creative commons license. Now how’s that for a turn on, whisky!

Health Canada report ties asbestos to lung cancer

Environment, Health No Responses »

Apr 162009

Health Canada sat for more than a year on a report by a panel of international experts that concludes there is a “strong relationship” between lung cancer and chrysotile asbestos mined in Canada.

Health Canada received the report in March 2008, resisting calls from the panel chairman to release the findings despite his plea last fall that the delay was “an annoying piece of needless government secrecy.”

Canwest News Service obtained the report under Access to Information legislation, but the request took more than 10 months to process.

Vancouver Sun

Yes, dog bites man anywhere else except Canada, which has a hard time accepting that it routinely exports products that kill people. The “annoying piece of needless government secrecy” is neither needless or annoying. It protects a dying industry with a few, powerful stakeholders in Quebec, an important swing political province, so there’s need for it! Annoying – your seat “buddy” on the bus yammering on their cellphone, cancer, well, I don’t know, you tell me!

Expect little to change from this report. It does mention that there is little danger from “Canadian exposure levels”, conveniently forgetting that 90% of the export is to developing countries where there are fewer safeguards. This feeds into the Canadian government line that “chrysotile” is safe if used correctly. If you think this line of reasoning is familiar, it is. The tobacco industry used it routinely till recently.

Shame.
n

Endocrine Disrupting Chemicals – A new Resource

Environment, Health No Responses »

Feb 092009

Critical Windows of Development is a timeline of how the human body develops in the womb, with animal research showing when low-dose exposure to endocrine disrupting chemicals during development results in altered health outcomes.

Critical Windows of Development

This promises to be an easy to use database showing development timelines of infants, and the documented effects of endocrine disrupting chemicals at these timelines. The prime focus is bisphenol A and phthalates at this point in time. The Environmental Health News has more about the program here. It is not out for public consumption yet, so stay tuned…

Autism epidemic not caused by shifts in diagnoses; environmental factors likely

Health No Responses »

Jan 092009

California’s sevenfold increase in autism cannot be explained by changes in doctors’ diagnoses and most likely is due to environmental exposures, University of California scientists reported. The scientists who authored the new study advocate a nationwide shift in autism research to focus on an array of potential factors in the environment that babies and fetuses are exposed to, including pesticides, viruses and chemicals in household products.

Autism epidemic not caused by shifts in diagnoses; environmental factors likely — Environmental Health News

One of the most common arguments you will see about a lot of mental health diagnoses is that doctors have changed their diagnostic practices significantly. While there is evidence of this occurring in diagnoses of childhood depression, anxiety, or even bipolar disorder due to the millions of dollars involved in medication and the attendant corruption, autism is different.

This population study used 17 year data in California and concluded that diagnostic changes were only responsible for a 2 fold increase, not the seven fold increase seen. The rest is unexplained, and the authors attribute it to a confluence of environmental and genetic factors.

And no, for the last time, VACCINES DO NOT CAUSE AUTISM!

Asbestos stays off global dangerous-substance list

Environment, Health No Responses »

Oct 292008

NDP MP Pat Martin said Tuesday the Canadian delegation did not even participate in the discussions this year but got others to work on their behalf instead.

He accused the Canadians of browbeating developing nations such as India, Pakistan and Vietnam — some of Canada's largest chrysotile customers — into opposing its inclusion on the list.

"It's not a proud day for our country," said Martin, who attended the convention and spoke by telephone from Rome.

via Chrysotile asbestos stays off global dangerous-substance list

Canadians can now breathe easy. The government did not even have to oppose a notification officially, other countries did it for them.

Older Entries

The Olive Ridley Crawl

High fructose corn syrup makes you fat

Al Franken is good for health

Sugar Pills, now more effective!

Soda = Fat

NC Smoking ban now inevitable?

Circumcision and AIDS – Revisited

Health Canada report ties asbestos to lung cancer

Endocrine Disrupting Chemicals – A new Resource

Autism epidemic not caused by shifts in diagnoses; environmental factors likely

Asbestos stays off global dangerous-substance list

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